How to convert an ordinary warehouse into a cold storage for medicines?

　　How to convert an ordinary warehouse into a cold storage for medicines? With the rapid progress of global pharmaceutical technology and the continuous improvement of public health awareness, the storage and preservation of drugs are facing unprecedented high standards and strict requirements. Especially in the preservation of biological preparations, vaccines and some special drugs, any slight fluctuation in temperature and humidity may cause irreversible effects on their efficacy and safety. Therefore, the transformation of the traditional ordinary warehouse into a cold storage with high-precision temperature and humidity control capability has become a key initiative of the pharmaceutical industry to protect the quality of drugs and patient safety.

　　1.Initial assessment and research

　　At the beginning of the transformation, it is necessary to set up a professional team consisting of building engineers, refrigeration experts and drug management specialists to conduct a comprehensive and detailed preliminary assessment of the existing warehouse. The assessment includes, but is not limited to, the structural stability of the warehouse, the performance evaluation of the existing insulation materials, the efficiency test of the ventilation system and potential space optimisation options. At the same time, in-depth research into the specific storage requirements of the target drugs is also required to provide an accurate basis for subsequent design.

　　2.Customised planning and design

　　Based on the results of the initial assessment, the team will begin to develop a detailed blueprint for the renovation plan and design. At this stage, the focus will be on the partitioned layout of the cold room to ensure that different types of drugs are stored in separate areas to avoid cross-contamination. In addition, a high-performance temperature control system will be designed, including precise temperature-controlled refrigeration units and intelligent temperature control systems, as well as temperature gradient control zones that may be required for specific drugs. For humidity control, advanced humidity regulating equipment will be used to ensure that the environmental humidity is stabilised within the appropriate range.

　　3. Strengthening heat preservation and insulation measures

　　In order to ensure the stability of the temperature inside the cold storage and energy-saving effect, the walls, roofs and floors of the warehouses will be comprehensively upgraded, and high-performance heat preservation materials, such as polyurethane foam boards and vacuum insulation boards, will be used to carry out multi-layer composite heat preservation treatment. At the same time, the doors and windows and other openings are sealed and transformed to reduce cold loss and improve the overall thermal insulation performance.

　　4. Installation of high-efficiency refrigeration and humidity adjustment system

　　Selection of refrigeration units and chillers in line with GMP standards, to ensure that the internal temperature of the cold storage can respond quickly and stably maintained within the set range. During the installation process, focus on the reasonable layout of the equipment and pipelines to reduce the impact on daily operations. At the same time, it is equipped with accurate humidity sensors and automatic humidification/dehumidification equipment to achieve intelligent regulation of humidity and ensure a better storage environment for medicines.

　　5.Ventilation and air purification system

　　In order to keep the air inside the cold storage fresh and hygienic, an efficient ventilation system is installed to ensure smooth air circulation and reduce the accumulation of pollutants and odours. For special medicines that require a high degree of cleanliness, air purification equipment, such as HEPA filters, should be introduced to further improve air quality.

　　6. Safety and energy saving at the same time

　　In the process of transformation, safety is always put in the first place, installing automatic fire alarm and fire extinguishing systems, as well as electrical safety protection devices, to ensure that the cold storage operation process is foolproof. At the same time, it actively responds to the national energy conservation and environmental protection policy, selects refrigeration equipment with high energy-efficiency level and heat preservation materials, and realises greater use of energy through the intelligent control system to reduce the operating cost and environmental burden.

　　Detailed deepening of transformation requirements

　　Temperature control: In addition to the basic 2℃ to 8℃ temperature range, for some special medicines, such as biological products, a lower storage temperature may be required, and even a deep-cooling environment below -20℃ is needed. Therefore, the temperature control system needs to be highly flexible and adjustable.

　　Humidity management: In addition to maintaining a stable humidity range, the impact of seasonal changes on humidity needs to be taken into account, and humidity setpoints need to be predicted and adjusted through intelligent algorithms to ensure that medicines are stored under better conditions for a long period of time.

　　Monitoring and Tracing: Establish a comprehensive environmental monitoring system to monitor the temperature, humidity, air quality and other key parameters in the cold storage 24 hours a day, and realise the historical tracing of the data to provide strong support for the quality management of drugs.

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